Christian McCaffrey, the 49ers’ star running back, missed Friday’s practice due to a calf issue that appeared during Thursday’s session. Although officially listed as questionable for Sunday’s opener against the Seattle Seahawks, McCaffrey stressed that he feels ready to play. He downplayed concerns, saying, “I feel great about where I’m at,” while acknowledging that limited practice often attracts media speculation.
During Friday’s practice, McCaffrey performed stretches and warmups on the sidelines under the supervision of Mike Sola, the team’s director of reconditioning. Unlike his usual routine, he did not join the running backs for individual drills or installation work. Head coach Kyle Shanahan confirmed that McCaffrey did not participate in the main practice but provided no further details about the injury.
McCaffrey Manages Health Carefully, Completing Training Camp While Avoiding Serious Calf Setbacks
McCaffrey described the calf issue as “nothing serious” and credited himself for not pushing through Thursday’s practice. Given his previous history of tendinitis and a torn PCL last season, the running back emphasized the importance of managing his health. He reported completing a full training camp without issues, reinforcing his confidence in being ready for Week 1.

The 49ers deliberately limited McCaffrey’s practice workload during training camp, giving him every third day off to reduce injury risk. This strategy, consistent with 2023, allowed him to stay healthy while other backs missed time. McCaffrey’s unexpected addition to the injury report on Thursday came despite him practicing earlier in the week and not appearing on Wednesday’s report.
Robinson ready to step up while Niners maintain depth without McCaffrey
If McCaffrey cannot play, Brian Robinson Jr., recently acquired from the Washington Commanders, is expected to take the lead role. Rookie Jordan James and backup Isaac Guerendo provide additional depth, although James is listed as doubtful due to a broken finger. Shanahan expressed confidence that the team is prepared to handle the situation without McCaffrey.
McCaffrey dismissed concerns about past injuries, including last year’s opening-week calf issue that eventually led to the injured reserve. He is fully focused on Sunday’s matchup against the Seahawks. Robinson also emphasized his readiness, preparing as if he could start at any moment, ensuring the 49ers’ backfield remains capable regardless of McCaffrey’s status.